写的 - 写的 - OnScreen Science, Inc.
1. The simulations of OnScreen Retrovirus use the 3D nucleic acid models of our highly regarded DNA apps to make memorable the crucial steps by which the reverse transcriptase enzyme complex of a retrovirus uses nucleotide building blocks of the host cell to copy the viral genome, initially on a single strand of RNA, to a newly constructed double-stranded DNA molecule, ready to be inserted into the host's DNA as a source of new copies of the virus.
2. Unlike other simulations you might see on the internet, this app shows how the DNA synthesis is at every stage a three-dimensional double-helix-forming process and that it involves several steps, which include the separation of strands and the relative movement of the strands to allow annealing to each other at complementary sections, the steps being dependent on three separate activities of the reverse transcriptase complex: RNA-dependent DNA synthesis, RNA degradation, and DNA-dependent DNA synthesis.
3. Background material on viruses, nucleic acids, and enzymes, as well as commentary on each new step in the process of copying the single strand of RNA into a double-stranded DNA molecule are at your fingertips in the app.
4. Since retrotransposons--which we all have in our DNA!--make use the very same steps to make new copies of their DNA through an intermediate RNA strand before inserting it at another spot in the cell's DNA, the app serves as a simulation of how they work as well.
5. You can run the simulations with automatic pauses at key steps for convenience in reading of the commentary for the steps or straight through, pausing only when desired.
6. Since a ball-and-stick model of nucleic acids is used for the simulations, this is not done at the level of atomic detail, but the simulations are never in conflict with the biochemistry.
7. The goal of this app is to convey the conceptual details of the viral genome transfer from RNA to DNA without requiring of the user a deep prior knowledge of molecular biology.
8. The role of the virus's nucleocapsid protein as enhancer of the annealing of strands is also indicated.
9. Whether for first-time learning, clarification of ideas previously encountered, or review, OnScreen Retrovirus is now at your service.
10. Updated for the future: 64-bit native code.
或按照以下指南在PC上使用 :
选择你的电脑版本:
软件安装要求:
可直接下载。下载如下:
现在,打开已安装的模拟器应用程序并查找其搜索栏。一旦找到它,请键入 OnScreen Retrovirus 在搜索栏并按搜索。点击 OnScreen Retrovirus应用程序图标。一个 窗口 OnScreen Retrovirus 在Play商店或应用程序商店将打开并且它将在您的模拟器应用程序中显示商店。现在,按下安装按钮并像在iPhone或Android设备上一样,您的应用程序将开始下载。现在我们都完成了。
你会看到一个名为“所有应用程序”的图标。
点击它,它会带你到一个包含所有已安装应用程序的页面。
你应该看到 图标。点击它并开始使用该应用程序。
下载 OnScreen Retrovirus 对于Mac OS (Apple)
下载 | 开发人员 | 评论 | 评分 |
---|---|---|---|
Free 对于Mac OS | OnScreen Science, Inc. | 2 | 5.00 |
在 Windows 11 上设置电脑和下载 OnScreen Retrovirus 应用的步骤:
OnScreen DNA Model
OnScreen DNA Model for iPhone
OnScreen DNA Model
OnScreen Gene Transcription
OnScreen DNA Replication
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