Liposome Suite for Pc

1. The user should follow the simple rule to ensure proper functionality: all known data should be provided in the following order: solution or solute name (optional) -> Mw (if needed) -> initial concentrations (must!) -> volumes (if known) -> molar ratios (if known) -> Total Molarity (if known) -> Total Volume (if known).

2. To save lipid molar mass data to the database, the fields for lipid name and molar mass should be filled in, followed by pressing “V” button.

3. For example: final molar concentration and lipid molar fractions (%) of the components can be adjusted at any time if molar concentrations of starting solutions and final suspension volume are provided.

4. The lipid molar mass entries can be edited by double clicking the specific entry and editing the value in molar mass field and the pressing the “V” button.

5. Watch the molar ratios to ensure that all starting components are included! Program will skip components for which insufficient data is provided! Thus, for example concentration in g/l cannot be included in calculations if Mw of solute is not provided.

6. are calculated based upon initial data provided, such as: initial concentrations of the stock solutions, initial volumes and desired molar ratios.

7. Once calculations are accomplished, the final lipid (and not only) formulation can be stored for future needs, by providing formulation name and pressing “v” button.

8. If lipid name exists in database, then application will suggest to autocomplete name and fill in molar mass field, as the name is typed.

9. If user updates molar ratios (percents only), program will not start calculations until sum of the ratios will be 100 exactly and obviously, not before than initial concentrations are provided.

10. App includes database to store lipids molar masses and formulations, comprising of various lipid solutions.

11. · Stock solutions of lipids (or any other compound) are mixed in appropriate molar ratios.

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