Last Updated by Giuliana Scarpati on 2025-03-12
1. Bruyere et Al elaborated a plan, where antifungals were given only to patients with a high risk of IC (CS≥3 points) and uncontrolled sepsis despite well-conducted antibiotic therapy for at least 2 days.
2. Clinical prediction scores have emerged but their poor positive predictive values could lead to overtreatment with antifungals.
3. American and European experts have recommended empirical antifungal therapy in high-risk patients in the ICU.
4. Accurate evaluation of risk factors for mortality may improve early appropriate therapeutic management.
5. This strategy could be implemented by the use of a dedicated app, to test its efficacy in large clinical settings.
6. Identifying this subset of patients thus appears very relevant.
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