T Calc for Pc

1. Additionally, the calculated free and bioavailable testosterone should not be relied upon in situations with potential massive interference by steroids binding to SHBG (e.g. in women during pregnancy, in men during treatment inducing high levels of DHT or Mesterolone.

2. The Free Testosterone and Bioavailable Testosterone Calculator application is designed to assist clinicians in accurately determining circulating bioactive testosterone levels.

3. The Free & Bioavailable Testosterone Calculator reduces the risk of errors that can occur when performing complicated calculations by hand.

4. Certain health conditions and medications, such as corticosteroids, can affect SHBG levels, impacting total serum testosterone concentration.

5. Testosterone and dihydrotestosterone (DHT) circulate in plasma unbound (free approximately 2-3 percent), bound to specific plasma proteins (SHBG), and weakly bound to non-specific proteins such as albumin.

6. Combining albumin, sex hormone-binding globulin (SHBG) and testosterone levels provides a more precise measurement of total serum testosterone concentration.

7. Bioavailable testosterone measurement includes the free plus the weakly bound.

8. Once lab values are in place, press the calculate button and let the Free & Bioavailable Calculator app do the math.

9. The SHBG-bound fraction is biologically inactive because of the high binding affinity of SHBG for testosterone.

10. Free testosterone measures the free fraction.

11. IMPORTANT LIMITATIONS: This calculator is an educational tool and should not be solely relied upon in making any clinical decision.

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